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Septi Purnamasari
Universitas Sriwijaya
Religion Agriculture, Biological Sciences & Forestry Arts Humanities Biochemistry, Genetics & Molecular Biology Economics, Econometrics & Finance Education Engineering Environmental Science Health Professions Immunology & microbiology Languange, Linguistic, Communication & Media Law, Crime, Criminology & Criminal Justice Medicine & Pharmacology Neuroscience Nursing Physics Public Health Social Sciences Other

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Journal : Experimental Student Experiences

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Effect of Action and Active Compounds of Leaf Vocational Leaf (Tristania Whitiana Griff.) on Bacteria Shigella Dysenteriae Septi Purnamasari; Salni Salni; Joko Marwoto; Masayu Farah Diba
Experimental Student Experiences Vol. 1 No. 4 (2023): April
Publisher : LPPM Sunan Doe

Show Abstract | Download Original | Original Source | Check in Google Scholar | DOI: 10.58330/ese.v1i4.200

Abstract

The purpose of this study was to determine the ability of the antibacterial activity of pelawan leaf fractions and active compounds against Shigella dysenteriae bacteria. This research includes in vitro laboratory experimental research. The subject of this research is the bacterium Shigella dysenteriae. The results showed that the MIC value of the n-hexane fraction against Shigella dysenteriae was 125 mg/ml and the MIC value of the active compound n-hexane fraction was 62.5 mg/ml. Determination of the class of active compounds from the purification of the n-hexane fraction of Pelawan leaves obtained flavonoid compounds. The concentration equivalence test showed that 1 mg/ml n-hexane fraction was equivalent to 0.004 mg/ml ampicillin against Shigella dysenteriae bacteria and 1 mg/ml active compound flavonoid was equivalent to 0.01 mg/ml ampicillin against Shigella dysenteriae bacteria. It can be concluded that the active fraction of n-hexane and its compounds have positive antibacterial effectiveness against Shigella dysenteriae bacteria.
Co-Authors Adnan Abadi Akhyar Dyni Zakyah Arwan Bin Laeto Bagus Eko Prasetya Eka H. Oktharina Ella Amalia, Ella Fahmil Ikhsan Taharu Heriyadi Manan Joko Marwoto Joko Marwoto Joko Marwoto Lusia Hayati Lusia Hayati Masayu Farah Diba Masayu Farah Diba Masayu Farah Diba Nabila Istighfarin Nita Parisa Putra, Hadrians Kesuma RACHMAT HIDAYAT Raissa Nurwany Rara Inggarsih Ratih Krisna Salni Salni Yuni Fitriayanti